Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716509 | 0.81 | LRRK2 (0.41) | FFAR1ADRA2AADRA2BADRA2CALKBH1 | |
| SCHEMBL15716702 | 0.77 | FFAR1 (0.40) | FFAR1ADRA2AADRA2BADRA2CALKBH1 | |
| SCHEMBL24843944 | 0.77 | CHRNB2 (0.43) | — | |
| SCHEMBL12260858 | 0.75 | FFAR1 (0.53) | FFAR1ADRA2AADRA2BADRA2CIGLV6-57 | |
| SCHEMBL28048770 | 0.75 | CFTR (0.48) | ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL19478477 | 0.74 | GCK (0.40) | FFAR1ADRA2AADRA2BADRA2CALKBH1 | |
| SCHEMBL6904351 | 0.72 | FFAR1 (0.61) | FFAR1ADRA2AADRA2BADRA2CIGLV6-57 | |
| SCHEMBL4363303 | 0.72 | FFAR1 (0.56) | FFAR1ADRA2AADRA2BADRA2CIGLV6-57 | |
| SCHEMBL16052301 | 0.72 | LPL (0.40) | FFAR1ADRA2AADRA2BADRA2CALKBH1 | |
| SCHEMBL1203044 | 0.71 | FFAR1 (0.39) | FFAR1ADRA2AADRA2BADRA2CALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970323-B1 | FUROPYRIDINES AS BROMODOMAIN INHIBITORS. | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO 2) LTD (GB) | 2017-10-18 | — | — | EP | disclosed |