SCHEMBL1947868

SCHEMBL1947868

O=C(Cc1cccc2ccccc12)Nc1cc(NC(=O)Cc2cccc3ccccc23)cc(NC(=O)Cc2cccc3ccccc23)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.68
▸ LMNA P02545 4/20 0.67
▸ KMT2A Q03164 8/20 0.66
▸ MEN1 O00255 7/20 0.66
▸ POLB P06746 1/20 0.65
▸ KDM4E B2RXH2 4/20 0.62
▸ HPGD P15428 2/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.62
▸ PTGER4 P35408 1/20 0.62
▸ MAPT P10636 3/20 0.60
▸ HDAC3 O15379 1/20 0.60
▸ HDAC4 P56524 1/20 0.60
▸ HDAC1 Q13547 1/20 0.60
▸ HDAC8 Q9BY41 1/20 0.60
▸ HDAC6 Q9UBN7 1/20 0.60
▸ TDP1 Q9NUW8 1/20 0.59
▸ GLA P06280 1/20 0.58
▸ PPARG P37231 1/20 0.58
▸ NCOA2 Q15596 1/20 0.58
▸ NCOA1 Q15788 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10079871 0.90 ALDH1A1 (0.72) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL14344582 0.86 KMT2A (0.64) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL13467798 0.84 KMT2A (0.63) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL14344586 0.84 KMT2A (0.62) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL13451636 0.84 KMT2A (0.63) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL14520097 0.83 MEN1 (0.66) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL3712070 0.83 ALDH1A1 (0.60) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL13576511 0.82 ALDH1A1 (0.63) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL13451626 0.81 PTPN1 (0.66) ALDH1A1LMNAKMT2AMEN1POLB
SCHEMBL7168525 0.81 LMNA (0.63) ALDH1A1LMNAKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 — — EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 — — US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 — — EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 — — US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 — — US disclosed
EP-2510047-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2012-10-17 — — EP disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 — — US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 — — US disclosed
WO-2011071718-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2011-06-16 — — WO disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 — — US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 — — US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 — — US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 — — US disclosed
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