Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079871 | 0.88 | ALDH1A1 (0.72) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL14344582 | 0.87 | KMT2A (0.64) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL14344586 | 0.85 | KMT2A (0.62) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL13467798 | 0.85 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL13451626 | 0.85 | PTPN1 (0.66) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL1947868 | 0.84 | ALDH1A1 (0.68) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL13576511 | 0.82 | ALDH1A1 (0.63) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL13561013 | 0.81 | LMNA (0.60) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL2183704 | 0.79 | WNT3A (0.67) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL1233241 | 0.79 | AKR1C3 (0.62) | KMT2AMEN1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264760-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Parasitic Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-20100022547-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Parasitic Infections | BRANDEIS UNIVERSITY (US) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264760-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Parasitic Infections | IMPDH1, IMPDH2, ITPA | KMT2A 2923/4885MEN1 3018/4885LMNA 3931/4885 |
| US-20100022547-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Parasitic Infections | IMPDH1, IMPDH2, ITPA | KMT2A 2923/4885MEN1 3018/4885LMNA 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.