SCHEMBL1947883

SCHEMBL1947883

Cc1cccc(CC(=O)Nc2cc(NC(=O)Cc3cccc(C)c3)cc(NC(=O)Cc3cccc(C)c3)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HPGD P15428 1/20 0.61
PSEN1 P49768 1/20 0.61
PSEN2 P49810 1/20 0.61
APH1B Q8WW43 1/20 0.61
NCSTN Q92542 1/20 0.61
APH1A Q96BI3 1/20 0.61
PSENEN Q9NZ42 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
PKM P14618 1/20 0.58
MAPK8 P45983 1/20 0.58
ANO1 Q5XXA6 1/20 0.57
GLS O94925 1/20 0.56
KCNQ2 O43526 1/20 0.56
NLRP3 Q96P20 1/20 0.55
CACNA1G O43497 1/20 0.54
CACNA1H O95180 1/20 0.54
CACNA1I Q9P0X4 1/20 0.54
P2RY14 Q15391 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26504485 0.87 PSEN1 (0.53) ALDH1A1KDM4EHPGDPSEN1PSEN2
SCHEMBL16199440 0.85 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDPSEN1PSEN2
SCHEMBL259620 0.83 ALDH1A1 (0.76) ALDH1A1KDM4EHPGDNLRP3NPC1
SCHEMBL16905381 0.82 HDAC8 (0.60) ALDH1A1L3MBTL1PKMMAPK8GLS
SCHEMBL13329815 0.82 L3MBTL1 (0.56) ALDH1A1KDM4EHPGDPSEN1PSEN2
SCHEMBL7235999 0.81 KMT2A (0.60) ALDH1A1KDM4EHPGDPSEN1PSEN2
SCHEMBL19226313 0.81 MEN1 (0.71) ALDH1A1KDM4EHPGDNLRP3KMT2A
Propane SCHEMBL11035550 0.81 ALDH1A1 (0.72) ALDH1A1KDM4EHPGDNLRP3NPC1
SCHEMBL3637149 0.81 AOC2 (0.58) ALDH1A1KDM4EHPGDPSEN1PSEN2
SCHEMBL16887473 0.80 PSEN1 (0.59) ALDH1A1KDM4EHPGDPSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed