SCHEMBL1950346

SCHEMBL1950346

CCCCNC(=O)CN(Cc1cccc(-c2cc(C)ccc2OCC(=O)O)c1)C(=O)OCCCC

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.47
FFAR1 O14842 12/20 0.41
PPARD Q03181 3/20 0.40
FSHR P23945 1/20 0.39
GYS1 P13807 1/20 0.38
PTPN1 P18031 3/20 0.38
LTB4R2 Q9NPC1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1948087 0.91 PTGDR2 (0.47) PTGDR2FFAR1PPARDFSHRGYS1
SCHEMBL1948540 0.91 FSHR (0.46) PTGDR2FFAR1PPARDFSHRGYS1
SCHEMBL1946723 0.89 PTGDR2 (0.51) PTGDR2FFAR1PPARDPTPN1LTB4R2
SCHEMBL3666427 0.87 FSHR (0.42) FSHR
SCHEMBL1948049 0.81 PTGDR2 (0.53) PTGDR2FFAR1PPARDLTB4R2
SCHEMBL1947892 0.81 FFAR1 (0.43) FFAR1PTPN1LTB4R2
SCHEMBL13769580 0.80 PTGDR2 (0.55) PTGDR2FFAR1PPARDPTPN1
SCHEMBL3671754 0.80 FSHR (0.47) FSHR
SCHEMBL3666582 0.77 EPHX2 (0.44) FSHR
SCHEMBL3674765 0.77 FSHR (0.42) FSHRGYS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US claimed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US disclosed
WO-2009089192-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS HCAR2, PAH, PTGES2 PTGDR2 15/4885FFAR1 202/4885PPARD 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.