Sugi Predict

Sugi Predict / Compounds / SCHEMBL1948087

SCHEMBL1948087

SCHEMBL1948087

CCCCNC(=O)CN(Cc1cccc(-c2cc(Cl)ccc2OCC(=O)O)c1)C(=O)OCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGDR2 Q9Y5Y4 3/20 0.47
▸ L3MBTL1 Q9Y468 4/20 0.43
▸ HTT P42858 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ EPHX2 P34913 1/20 0.40
▸ PPARG P37231 1/20 0.40
▸ PPARA Q07869 1/20 0.40
▸ FFAR1 O14842 6/20 0.40
▸ TDP1 Q9NUW8 1/20 0.39
▸ FSHR P23945 1/20 0.39
▸ SLC6A9 P48067 1/20 0.39
▸ PLA2G1B P04054 1/20 0.38
▸ ATG4B Q9Y4P1 1/20 0.38
▸ PPARD Q03181 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ PTGER1 P34995 1/20 0.38
▸ GYS1 P13807 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950346 0.91 PTGDR2 (0.47) PTGDR2FFAR1FSHRPPARDGYS1
SCHEMBL1948540 0.90 FSHR (0.46) PTGDR2L3MBTL1HTTALDH1A1LMNA
SCHEMBL1946723 0.88 PTGDR2 (0.51) PTGDR2PPARGPPARAFFAR1PPARD
SCHEMBL3666582 0.87 EPHX2 (0.44) L3MBTL1ALDH1A1EPHX2PPARGPPARA
SCHEMBL13770250 0.81 PTGDR2 (0.54) PTGDR2L3MBTL1HTTTP53MAPT
SCHEMBL1948049 0.80 PTGDR2 (0.53) PTGDR2PPARGPPARAFFAR1PPARD
SCHEMBL3671754 0.80 FSHR (0.47) ALDH1A1EPHX2FSHR
SCHEMBL1947892 0.78 FFAR1 (0.43) L3MBTL1HTTALDH1A1LMNAFFAR1
SCHEMBL3666427 0.77 FSHR (0.42) ALDH1A1EPHX2PPARAFSHR
SCHEMBL3674765 0.77 FSHR (0.42) ALDH1A1EPHX2FSHRGYS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US claimed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 — — US disclosed
WO-2009089192-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2009-07-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS HCAR2, PAH, PTGES2 PTGDR2 15/4885L3MBTL1 4411/4885HTT 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.