Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL5709392 | 0.93 | GPR84 (0.65) | GPR84FFAR1FFAR4TP53CAMK2A | |
| 1,6-Hexanediol SCHEMBL3482818 | 0.91 | GPR84 (0.70) | GPR84FFAR1FFAR4TP53CAMK2A | |
| Lactic Acid SCHEMBL3038365 | 0.91 | GPR84 (0.70) | GPR84FFAR1FFAR4TP53CAMK2A | |
| Oxybate SCHEMBL1643115 | 0.91 | CAMK2A (0.67) | GPR84FFAR1FFAR4TP53CAMK2A | |
| Lactic Acid SCHEMBL8850880 | 0.90 | TP53 (0.65) | GPR84FFAR1FFAR4TP53CAMK2A | |
| Lactic Acid SCHEMBL11019396 | 0.90 | TP53 (0.65) | GPR84FFAR1FFAR4TP53CAMK2A | |
| Lactic Acid SCHEMBL3846619 | 0.87 | TP53 (0.61) | GPR84FFAR1FFAR4TP53CAMK2A | |
| 1,6-Hexanediol SCHEMBL3482973 | 0.87 | TP53 (0.61) | GPR84FFAR1FFAR4TP53CAMK2A | |
| Succinic Acid SCHEMBL15949792 | 0.87 | TP53 (0.69) | TP53CYP1A2LMNAALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL935212 | 0.87 | TP53 (0.69) | TP53CYP1A2LMNAALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925997-B1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEM CORP (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-11732087-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-08-22 | — | — | US | disclosed |
| EP-3925998-B1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEM CORP (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-20230124462-A1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-04-20 | — | — | US | disclosed |
| US-11560449-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-01-24 | — | — | US | disclosed |
| EP-3925998-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3925997-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3925996-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3919543-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-12-08 | — | — | EP | disclosed |
| EP-3909998-A2 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | Mitsubishi Chemical Corporation (JP) | 2021-11-17 | — | — | EP | disclosed |
| EP-2366726-A2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366727-A2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-8021864-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-20 | — | — | US | disclosed |
| EP-2365017-A2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-7985566-B2 | Biomass-resource-derived polyester and production process thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110009531-A1 | a dicarboxylic acid and/or a diol derived from biomass resources; capable of suppressing hydrolysis; environmentally friendly; eco-friendly | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2204396-A1 | Biomass-resource derived polyester and production process thereof | Mitsubishi Chemical Corporation (JP) | 2010-07-07 | — | — | EP | disclosed |
| EP-1882712-B1 | BIOMASS-RESOURCE-DERIVED POLYESTER AND PRODUCTION PROCESS THEREOF | MITSUBISHI CHEM CORP (JP) | 2010-04-21 | — | — | EP | disclosed |
| US-20090171037-A1 | a dicarboxylic acid and/or a diol derived from biomass resources; capable of suppressing hydrolysis; environmentally friendly; eco-friendly | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1882712-A1 | POLYESTER DERIVED FROM BIOMASS RESOURCES AND METHOD FOR PRODUCTION THEREOF | Mitsubishi Chemical Corporation (JP) | 2008-01-30 | — | — | EP | disclosed |