Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510641 | 0.90 | RAB9A (0.70) | MAPTPOLBRAB9AGAAALDH1A1 | |
| SCHEMBL9237734 | 0.89 | RAB9A (0.61) | MAPTTDP1POLBRAB9AGAA | |
| SCHEMBL9237730 | 0.89 | RAB9A (0.61) | MAPTTDP1POLBRAB9AGAA | |
| SCHEMBL22384242 | 0.89 | LNPEP (0.55) | MAPTTDP1POLBROCK2CTSL | |
| SCHEMBL15037126 | 0.89 | LNPEP (0.55) | MAPTTDP1POLBROCK2CTSL | |
| SCHEMBL15096411 | 0.89 | MAPT (0.49) | MAPTTDP1POLBRAB9AGAA | |
| SCHEMBL8165005 | 0.85 | PTPN1 (0.67) | MAPTRAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL8165003 | 0.85 | PTPN1 (0.67) | MAPTRAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL28294750 | 0.85 | MAPT (0.50) | MAPTTDP1POLBRAB9AGAA | |
| SCHEMBL28294749 | 0.85 | MAPT (0.50) | MAPTTDP1POLBRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |