SCHEMBL194855

SCHEMBL194855

C=C(C)C(=O)OCC(CO)(CO)COC(=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
THRB P10828 1/20 0.39
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL1463859 0.93 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL33308 0.92 TSHR (0.47) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL463327 0.90 TSHR (0.45) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL2454708 0.90 TSHR (0.45) TSHRALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL6846562 0.89 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL6678734 0.89 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL5799367 0.89 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL4075755 0.89 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL4614167 0.89 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1
Methacrylic Acid SCHEMBL11166297 0.89 TSHR (0.41) TSHRALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 EP disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 EP disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3914965-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2021-12-01 EP disclosed
WO-2021175855-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-09-10 WO disclosed
US-10793555-B2 Oxime ester photoinitiators BASF SE (DE) 2020-10-06 US disclosed
EP-1778636-B1 OXIME ESTER PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2007-12-19 EP disclosed
WO-2007071497-A1 OXIME ESTER PHOTOINITIATORS CIBA HOLDING INC. (CH) 2007-06-28 WO disclosed
EP-1794240-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2007-06-13 EP disclosed
WO-2007062963-A1 OXIME ESTER PHOTOINITIATORS CIBA HOLDING INC. (CH) 2007-06-07 WO disclosed
EP-1778636-A1 OXIME ESTER PHOTOINITIATORS Ciba SC Holding AG (CH) 2007-05-02 EP disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
WO-2006037728-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-13 WO disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TSHR 528/4885ALDH1A1 823/4885TP53 2497/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TSHR 519/4885ALDH1A1 779/4885TP53 2415/4885
US-10793555-B2 Oxime ester photoinitiators NR2E3, OXER1, CBR3 TSHR 310/4885ALDH1A1 929/4885TP53 4385/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TSHR 528/4885ALDH1A1 823/4885TP53 2497/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 TSHR 2202/4885ALDH1A1 964/4885TP53 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.