Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.36 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.36 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.36 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.36 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.36 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 3/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20426109 | 0.95 | MME (0.34) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL22449029 | 0.92 | MME (0.35) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL22449139 | 0.92 | MME (0.36) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL22449182 | 0.92 | MME (0.36) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL22449274 | 0.91 | CA2 (0.34) | GCGRMMEDGAT1KIFC1 | |
| SCHEMBL22449186 | 0.87 | HPGD (0.41) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL15037083 | 0.87 | HPGD (0.41) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL15037080 | 0.87 | HPGD (0.41) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL17834867 | 0.84 | KIFC1 (0.43) | MMEDGAT1ACEACE2KIFC1 | |
| SCHEMBL15037392 | 0.84 | KIFC1 (0.43) | MMEDGAT1ACEACE2KIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |