Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.32 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449139 | 0.94 | MME (0.36) | MMEDGAT1KIFC1COPS5MCL1 | |
| SCHEMBL22449029 | 0.93 | MME (0.35) | MMEDGAT1KIFC1COPS5MCL1 | |
| SCHEMBL19485661 | 0.92 | GCGR (0.37) | MMEDGAT1KIFC1ACEACE2 | |
| SCHEMBL20426109 | 0.91 | MME (0.34) | MMEDGAT1KIFC1COPS5MCL1 | |
| SCHEMBL22449274 | 0.90 | CA2 (0.34) | MMEDGAT1KIFC1GCGRALDH1A1 | |
| SCHEMBL17968745 | 0.86 | KIFC1 (0.43) | MMEDGAT1KIFC1MCL1ACE | |
| SCHEMBL15037133 | 0.86 | KIFC1 (0.43) | MMEDGAT1KIFC1MCL1ACE | |
| SCHEMBL17834867 | 0.86 | KIFC1 (0.43) | MMEDGAT1KIFC1MCL1ACE | |
| SCHEMBL15037392 | 0.86 | KIFC1 (0.43) | MMEDGAT1KIFC1MCL1ACE | |
| SCHEMBL22384390 | 0.86 | KLKB1 (0.39) | MMEDGAT1KIFC1MCL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |