Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12142803 | 1.00 | KMT2A (0.55) | KMT2ALMNAHSD17B10PPARGPPARA | |
| SCHEMBL11237591 | 0.88 | TBXAS1 (0.59) | LMNATBXAS1HPGDPTGS1PTGS2 | |
| SCHEMBL11632648 | 0.86 | KMT2A (0.57) | KMT2ALMNAHSD17B10PPARGPPARA | |
| SCHEMBL14640265 | 0.86 | ALDH1A1 (0.55) | KMT2ALMNAPPARGTBXAS1ACACB | |
| SCHEMBL24294931 | 0.85 | TBXAS1 (0.48) | LMNAPPARGTBXAS1ACACBEPHX2 | |
| SCHEMBL13594789 | 0.85 | TBXAS1 (0.51) | LMNAPPARGTBXAS1ACACBEPHX2 | |
| SCHEMBL15905964 | 0.85 | TBXAS1 (0.51) | LMNAPPARGTBXAS1ACACBEPHX2 | |
| SCHEMBL24295254 | 0.84 | TBXAS1 (0.47) | LMNAPPARGPPARATBXAS1ACACB | |
| SCHEMBL13594791 | 0.82 | EPHX2 (0.46) | KMT2ALMNAPPARGTBXAS1ACACB | |
| SCHEMBL585471 | 0.82 | LMNA (0.64) | KMT2ALMNAHSD17B10ACACBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9797908-B2 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-24 | — | — | US | disclosed |