Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.39 |
| ▸ | RET | P07949 | 12/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19481945 | 1.00 | MC4R (0.39) | MC4RRETKITALDH1A1 | |
| SCHEMBL19486482 | 0.94 | DRD2 (0.38) | MC4RRETKIT | |
| SCHEMBL19481973 | 0.94 | DRD2 (0.38) | MC4RRETKIT | |
| SCHEMBL19481972 | 0.94 | DRD2 (0.38) | MC4RRETKIT | |
| SCHEMBL19486841 | 0.94 | DRD2 (0.38) | MC4RRETKIT | |
| SCHEMBL19459170 | 0.94 | MC4R (0.40) | MC4RRETKITALDH1A1 | |
| SCHEMBL25155081 | 0.93 | MC4R (0.39) | MC4RRETKIT | |
| SCHEMBL21678202 | 0.93 | KIT (0.36) | MC4RRETKITALDH1A1 | |
| SCHEMBL19481907 | 0.89 | BMPR1B (0.38) | MC4RRETKIT | |
| SCHEMBL19481905 | 0.89 | BMPR1B (0.38) | MC4RRETKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298069-A1 | INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | BLUEPRINT MEDICINES CORPORATION | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298069-A1 | INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | ACVR1, ACVR2A, ACVRL1 | MC4R 3673/4885RET 50/4885KIT 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.