Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.96 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.75 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639467 | 1.00 | ESR1 (0.96) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL1948714 | 1.00 | ESR1 (0.96) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL641985 | 0.98 | ESR1 (1.00) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL14354218 | 0.93 | ESR1 (0.83) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| Phenol SCHEMBL18863020 | 0.93 | ESR1 (0.83) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL4612465 | 0.91 | ESR1 (0.78) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL55433 | 0.89 | ESR1 (0.74) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL22046628 | 0.87 | ESR1 (0.72) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| Phosphine SCHEMBL28461311 | 0.86 | ESR1 (0.71) | ESR1ESR2CYP19A1CYP11B2PTGS2 | |
| SCHEMBL30366689 | 0.86 | ESR1 (0.71) | ESR1ESR2CYP19A1CYP11B2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402398-B | Carbon dot precursor based on aggregation-induced emission effect, carbon dot, and preparation method and application thereof | 湖北大学 | 2022-10-28 | — | — | CN | claimed |
| CN-112745236-B | Diamine monomer containing tetraphenylethylene-triphenylamine structure, preparation method and application of diamine monomer in preparation of colorless polyimide | 吉林大学 | 2021-12-24 | — | — | CN | claimed |
| CN-113402398-A | Carbon dot precursor based on aggregation-induced emission effect, carbon dot, and preparation method and application thereof | 湖北大学 | 2021-09-17 | — | — | CN | claimed |
| CN-112745236-A | Diamine monomer containing tetraphenylethylene-triphenylamine structure, preparation method and application of diamine monomer in preparation of colorless polyimide | 吉林大学 | 2021-05-04 | — | — | CN | claimed |
| CN-109575230-B | Preparation method and application of multifunctional polyurethane derivative | 黑龙江大学 | 2021-01-22 | — | — | CN | claimed |
| CN-109336787-B | Preparation method and application of multifunctional polyurethane derivative containing triarylamine structure and tetraphenylethylene group | 黑龙江大学 | 2021-01-22 | — | — | CN | claimed |
| CN-109400836-B | Preparation method and application of polyurethane derivative containing triarylamine structure and tetraphenylethylene group | 黑龙江大学 | 2021-01-22 | — | — | CN | claimed |
| CN-111909370-A | High-performance fluorescent functionalized poly (arylene ether nitrile) and preparation method and application thereof | 成都大学 | 2020-11-10 | — | — | CN | claimed |
| CN-1386440-A | Health-care food for regulating blood sugar and blood fat | CAO ZHIGUO (CN) | 2002-12-25 | — | — | CN | claimed |
| CN-1386500-A | Application of diphenylvinyl phenol glucoside compounds in preparing hypoglycemic medicine | CAO ZHIGUO (CN) | 2002-12-25 | — | — | CN | claimed |
| CN-1386499-A | Application of diphenylvinyl phenol glucosides in preparing hypolipemic medicine | CAO ZHIGUO (CN) | 2002-12-25 | — | — | CN | claimed |
| CN-114920904-B | Preparation method and application of colorless transparent high-strength polyurethane anti-counterfeiting material | 郑州大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115624032-A | Preparation method of prochloraz-epoxiconazole water emulsion | 江苏剑牌农化股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-113402398-B | Carbon dot precursor based on aggregation-induced emission effect, carbon dot, and preparation method and application thereof | 湖北大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-114920904-A | Preparation method and application of colorless transparent high-strength polyurethane anti-counterfeiting material | 郑州大学 | 2022-08-19 | — | — | CN | disclosed |
| EP-0794771-A1 | METHOD OF USING TRIARYL-ETHYLENE DERIVATIVES IN THE TREATMENT AND PREVENTION OF OSTEOPOROSIS | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0720597-A1 | TRIARYL-ETHYLENE DERIVATIVES FOR USE IN THERAPY | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5525633-A | ANTITUMOR AGENTS, ANTICHOLESTEROL AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1996016646-A1 | METHOD OF USING TRIARYL-ETHYLENE DERIVATIVES IN THE TREATMENT AND PREVENTION OF OSTEOPOROSIS | HOECHST MARION ROUSSEL, INC. (US) | 1996-06-06 | — | — | WO | disclosed |
| WO-1995008528-A1 | TRIARYL-ETHYLENE DERIVATIVES FOR USE IN THERAPY | MERRELL PHARMACEUTICALS INC. (US) | 1995-03-30 | — | — | WO | disclosed |