SCHEMBL19487466

SCHEMBL19487466

CCC(=O)[C@H](CCCCNC)NC(C)C

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 1/20 0.38
▸ EPHX1 P07099 2/20 0.33
▸ CPB2 Q96IY4 1/20 0.33
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ CTSK P43235 1/20 0.31
▸ SIRT6 Q8N6T7 1/20 0.31
▸ SIRT1 Q96EB6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24221255 1.00 KISS1R (0.38) KISS1REPHX1CPB2MEN1KMT2A
SCHEMBL19545990 0.86 KDM4E (0.34) EPHX1MEN1KMT2ACTSKSIRT6
SCHEMBL22951230 0.84 KISS1R (0.37) KISS1REPHX1CPB2MEN1KMT2A
SCHEMBL23707734 0.84 KISS1R (0.37) KISS1REPHX1CPB2MEN1KMT2A
SCHEMBL20235709 0.83 KDM4E (0.47) EPHX1MEN1KMT2ASIRT6SIRT1
SCHEMBL24157441 0.82 KISS1R (0.47) KISS1REPHX1CPB2SIRT6SIRT1
SCHEMBL24410436 0.82 CPB2 (0.40) KISS1RCPB2MEN1KMT2A
SCHEMBL21297374 0.81 KISS1R (0.39) KISS1REPHX1CPB2
SCHEMBL14252281 0.81 KISS1R (0.35) KISS1REPHX1CPB2MEN1KMT2A
SCHEMBL16692066 0.81 KISS1R (0.39) KISS1REPHX1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10626144-B2 Peptide derivatives and uses thereof NOSOPHARM (FR) 2020-04-21 — — US disclosed
US-20170298097-A1 Peptide Derivatives and Uses Thereof NOSOPHARM (FR) 2017-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626144-B2 Peptide derivatives and uses thereof VIP, IAPP, NGLY1 KISS1R 381/4885EPHX1 4301/4885CPB2 236/4885
US-20170298097-A1 Peptide Derivatives and Uses Thereof VIP, IAPP, NGLY1 KISS1R 381/4885EPHX1 4301/4885CPB2 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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