Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338293 | 0.94 | KISS1R (0.53) | KISS1R | |
| SCHEMBL21297374 | 0.87 | KISS1R (0.39) | KISS1RCPB2EPHX1 | |
| SCHEMBL27309897 | 0.87 | KISS1R (0.39) | KISS1RCPB2SIRT6SIRT1EPHX1 | |
| SCHEMBL16692066 | 0.87 | KISS1R (0.39) | KISS1RCPB2EPHX1 | |
| SCHEMBL22800098 | 0.85 | KDM4E (0.35) | KISS1RFOLH1SIRT6SIRT1EPHX1 | |
| SCHEMBL22799569 | 0.85 | KDM4E (0.35) | KISS1RFOLH1SIRT6SIRT1EPHX1 | |
| SCHEMBL24410436 | 0.85 | CPB2 (0.40) | KISS1RCPB2FOLH1SMN1; SMN2KDM4A | |
| SCHEMBL20235708 | 0.84 | KDM4E (0.52) | FOLH1SIRT6SIRT1EPHX1SMN1; SMN2 | |
| SCHEMBL14525109 | 0.82 | KISS1R (0.47) | KISS1RCPB2FOLH1SIRT6SIRT1 | |
| SCHEMBL10026152 | 0.82 | KISS1R (0.47) | KISS1RCPB2FOLH1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023290-A1 | THERAPEUTIC DENDRIMER | STARPHARMA PTY LTD. (AU) | 2022-01-27 | — | — | US | disclosed |
| US-20210403648-A1 | THERAPEUTIC DENDRIMER | STARPHARMA PTY LTD. (AU) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220023290-A1 | THERAPEUTIC DENDRIMER | DCK, PAICS, DCLRE1A | KISS1R 2367/4885CPB2 3863/4885FOLH1 136/4885 |
| US-20210403648-A1 | THERAPEUTIC DENDRIMER | CLTA, DCK, CLTB | KISS1R 1610/4885CPB2 2241/4885FOLH1 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.