Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200239 | 0.95 | GABRG2 (0.40) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL571669 | 0.85 | PTGES (0.44) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL571668 | 0.85 | PTGES (0.44) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL12373570 | 0.83 | GABRA1 (0.42) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL10201501 | 0.83 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL12373582 | 0.83 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL12373508 | 0.81 | HCRTR1 (0.37) | HCRTR1HCRTR2JAK1CHEK2 | |
| SCHEMBL12373604 | 0.80 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL12558673 | 0.79 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL12558668 | 0.79 | HCRTR1 (0.43) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |