Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201488 | 0.83 | L3MBTL1 (0.40) | GABRG2GABRB3GABRA5GABRA6GABRA1 | |
| SCHEMBL10201148 | 0.80 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA6GABRA1 | |
| SCHEMBL12373604 | 0.79 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA6GABRA1 | |
| SCHEMBL19488569 | 0.77 | MAPK1 (0.31) | — | |
| SCHEMBL12295805 | 0.77 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA6GABRA1 | |
| SCHEMBL10200232 | 0.77 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA6GABRA1 | |
| SCHEMBL19488632 | 0.76 | MEN1 (0.37) | GRM5MEN1KMT2A | |
| SCHEMBL10201154 | 0.76 | GABRG2 (0.34) | GABRG2GABRB3GABRA5GABRA6GABRA1 | |
| SCHEMBL19488864 | 0.74 | MEN1 (0.36) | GRM5MEN1KMT2A | |
| SCHEMBL19488328 | 0.74 | CHEK2 (0.42) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |