Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201174 | 0.89 | HCRTR1 (0.43) | HCRTR1HCRTR2CHEK2 | |
| SCHEMBL19488784 | 0.89 | UCHL1 (0.41) | L3MBTL1PTGESHCRTR1HCRTR2GABRG2 | |
| SCHEMBL6125919 | 0.86 | HCRTR1 (0.44) | L3MBTL1PTGESHCRTR1HCRTR2CHEK2 | |
| SCHEMBL6125920 | 0.86 | HCRTR1 (0.44) | L3MBTL1PTGESHCRTR1HCRTR2CHEK2 | |
| SCHEMBL203894 | 0.86 | HCRTR1 (0.47) | L3MBTL1PTGESHCRTR1HCRTR2CHEK2 | |
| SCHEMBL2706317 | 0.86 | HCRTR1 (0.47) | L3MBTL1PTGESHCRTR1HCRTR2CHEK2 | |
| SCHEMBL10201148 | 0.86 | GABRG2 (0.35) | L3MBTL1GABRG2GABRB3GABRA5GABRA6 | |
| SCHEMBL12373604 | 0.85 | GABRG2 (0.35) | GABRG2GABRB3GABRA5GABRA6GABRA4 | |
| SCHEMBL571669 | 0.84 | PTGES (0.44) | L3MBTL1PTGESHCRTR1HCRTR2GABRG2 | |
| SCHEMBL571668 | 0.84 | PTGES (0.44) | L3MBTL1PTGESHCRTR1HCRTR2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |