SCHEMBL1948889

SCHEMBL1948889

O=C(CC1CCCC1)Nc1cc(NC(=O)CC2CCCC2)cc(NC(=O)CC2CCCC2)c1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.69
RAB9A P51151 4/20 0.69
EPHX2 P34913 4/20 0.69
KMT2A Q03164 4/20 0.69
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2D6 P10635 1/20 0.64
HPGD P15428 1/20 0.64
CYP2C19 P33261 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
TDP1 Q9NUW8 1/20 0.62
MEN1 O00255 2/20 0.60
TSHR P16473 1/20 0.57
NAMPT P43490 2/20 0.54
AAK1 Q2M2I8 1/20 0.53
ALPL P05186 1/20 0.51
POLB P06746 1/20 0.51
EPHX1 P07099 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950761 0.98 EPHX2 (0.72) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL22270328 0.86 EPHX2 (0.57) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL6567255 0.85 EPHX2 (0.59) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL13568424 0.84 EPHX2 (0.59) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL4866294 0.83 EPHX2 (0.97) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL3822162 0.82 EPHX2 (1.00) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL17896781 0.81 RAB9A (0.54) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL1948582 0.81 ALDH1A1 (0.64) NPC1RAB9AKMT2ACYP1A2CYP3A4
SCHEMBL5308393 0.80 RAB9A (0.73) NPC1RAB9AEPHX2KMT2ACYP1A2
SCHEMBL3709185 0.80 RAB9A (0.73) NPC1RAB9AEPHX2KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed