Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 10/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971552 | 0.72 | MAPT (0.51) | HTT | |
| SCHEMBL26640445 | 0.70 | MAPT (0.47) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL1948887 | 0.68 | ALDH1A1 (0.48) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL27527421 | 0.68 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL26640744 | 0.68 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL20704061 | 0.68 | HIF1A (0.38) | HTT | |
| SCHEMBL1952644 | 0.67 | TDP2 (0.44) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL28292428 | 0.67 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL6966089 | 0.66 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL28408084 | 0.66 | DPP7 (0.46) | PNMTADRA2AADRA2BADRA2CTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168966-B1 | BICYCLOANILINE DERIVATIVE | MSD KK (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-8436004-B2 | Bicycloaniline derivative | MSD K.K. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20110135601-A1 | BICYCLOANILINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2011-06-09 | — | — | US | disclosed |
| EP-2168966-A1 | BICYCLOANILINE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110135601-A1 | BICYCLOANILINE DERIVATIVE | WEE1, WEE2, CCNK | PNMT 4222/4885ADRA2A 1792/4885ADRA2B 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.