SCHEMBL1948906

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1953181	0.83	PNMT (0.56)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL1950885	0.75	PNMT (0.54)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL1950552	0.75	TDP2 (0.58)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL12827583	0.74	PNMT (0.49)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL717840	0.74	PNMT (0.81)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL22542192	0.74	PARP10 (0.42)	ADRA2AMAPT
	Hydrochloric Acid SCHEMBL1947220	0.72	PNMT (0.78)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL22545336	0.72	ALDH1A1 (0.31)	MAPT
	SCHEMBL2884784	0.72	PNMT (0.44)	PNMTADRA2ATDP2ADRA2BADRA2C
	SCHEMBL324460	0.71	PNMT (1.00)	PNMTADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.