SCHEMBL194891

SCHEMBL194891

[CH2]C(O)(OC=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.38
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
KCNN4 O15554 1/20 0.35
CYP1A2 P05177 2/20 0.34
ALOX15 P16050 1/20 0.34
HTT P42858 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CES1 P23141 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CHRM3 P20309 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25767489 0.78 PTPN1 (0.40) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL28647026 0.73 PTPN1 (0.36) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL183490 0.73 KIF11 (0.40) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL2201549 0.71 CYP1A2 (0.44) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL6295381 0.71 CES1 (0.44) ALDH1A1TSHRKCNN4CYP1A2ALOX15
SCHEMBL863162 0.70 KDM4E (0.44) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL28246800 0.70 KCNN4 (0.44) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL28298597 0.70 ALDH1A1 (0.39) PTPN1ALDH1A1TSHRKCNN4CYP1A2
SCHEMBL131979 0.70 TDP1 (0.46) PTPN1ALDH1A1KCNN4ALOX15CYP2C19
SCHEMBL135668 0.70 MAPK1 (0.56) PTPN1ALDH1A1KCNN4ALOX15CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 EP disclosed
EP-3354641-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-08-01 EP disclosed
US-20040170924-A1 Oxime ester photoiniators having a combined structure CIBA CORPORATION 2004-09-02 US disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 EP disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 PTPN1 1422/4885ALDH1A1 823/4885TSHR 528/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 PTPN1 1422/4885ALDH1A1 823/4885TSHR 528/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 PTPN1 1466/4885ALDH1A1 779/4885TSHR 519/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 PTPN1 3052/4885ALDH1A1 2225/4885TSHR 333/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 PTPN1 1422/4885ALDH1A1 823/4885TSHR 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.