Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL8899755 | 1.00 | TTR (0.60) | TTRLMNAALDH1A1MEN1KMT2A | |
| Dioxane SCHEMBL9456670 | 0.88 | TTR (0.46) | TTRLMNAALDH1A1MEN1KMT2A | |
| Tetrahydrofuran SCHEMBL193538 | 0.82 | — | — | |
| Dioxane SCHEMBL3093215 | 0.82 | ALDH1A1 (0.50) | TTRALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11207601 | 0.78 | TTR (1.00) | TTRLMNAALDH1A1MEN1KMT2A | |
| Dioxane SCHEMBL9836999 | 0.78 | — | — | |
| Dioxane SCHEMBL3631647 | 0.78 | TTR (1.00) | TTRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL78595 | 0.78 | TTR (1.00) | TTRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16041435 | 0.78 | TTR (1.00) | TTRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1119 | 0.78 | TTR (1.00) | TTRLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603052-A | Ester derivative of (iso) eugenol and preparation method and application thereof | 中国农业大学 | 2024-02-27 | — | — | CN | claimed |
| WO-2023207894-A1 | POLYMORPH FORMS OF A 5H-PYRROLO [2, 3-b] PYRAZINE DERIVATIVE, METHODS OF PREPARATION, AND USES THEREFORE | BEIGENE , LTD. (KY) | 2023-11-02 | — | — | WO | claimed |
| CN-102921193-B | Preparation method of capillary electro-chromatography column taking beta-cyclodextrin as bonded stationary phase and application in chiral drug separation | UNIV ZHENGZHOU | 2015-03-18 | — | — | CN | claimed |
| CN-102512849-B | Preparation method of capillary packed column | UNIV ZHENGZHOU | 2014-04-09 | — | — | CN | claimed |
| CN-102512849-A | Preparation method of capillary packed column | UNIV ZHENGZHOU | 2012-06-27 | — | — | CN | claimed |
| JP-4718177-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| CN-101463106-B | Copolymer film forming resin containing benzoxazine structure and deep UV negativity chemical amplification type photo resist | CHENGDU JINJIANG HI TECH MATERIAL CO LTD | 2010-07-28 | — | — | CN | claimed |
| CN-101463106-A | Copolymer film forming resin containing benzoxazine structure and deep UV negativity chemical amplification type photo resist | CHENGDU JINJIANG HI TECH MATER (CN) | 2009-06-24 | — | — | CN | claimed |
| US-7405323-B2 | Modafinil polymorphic forms | CEPHALON FRANCE (FR) | 2008-07-29 | — | — | US | claimed |
| US-20060252835-A1 | treatment of sleep disorders with five novel polymorphic forms of modafinil racemate called CRL 40476 form III, CRL 40476 form IV, CRL 40476 form V, CRL 40476 form VI, CRL 40476 form VII; preparing a new solvate of modafinil comprising dissolving in solvent and crystallizing | CEPHALON FRANCE (FR) | 2006-11-09 | — | — | US | claimed |
| CN-1675177-A | Modafinil polymorphic forms | CEPHALON FRANCE (FR) | 2005-09-28 | — | — | CN | claimed |
| US-20040102523-A1 | Modafinil polymorphic forms | TEVA SANTE (FR) | 2004-05-27 | — | — | US | claimed |
| CN-117603052-A | Ester derivative of (iso) eugenol and preparation method and application thereof | 中国农业大学 | 2024-02-27 | — | — | CN | disclosed |
| WO-2024002786-A1 | SULFONATED AND SULFATED ARYL-ALKYL COMPOUNDS USEFUL AS SURFACTANTS | SPECIALTY OPERATIONS FRANCE (FR) | 2024-01-04 | — | — | WO | disclosed |
| WO-2023207894-A1 | POLYMORPH FORMS OF A 5H-PYRROLO [2, 3-b] PYRAZINE DERIVATIVE, METHODS OF PREPARATION, AND USES THEREFORE | BEIGENE , LTD. (KY) | 2023-11-02 | — | — | WO | disclosed |
| CN-114478451-A | 6- (hydroxybenzyloxy) phthalide Mannich base compound, preparation method and application thereof | 四川大学 | 2022-05-13 | — | — | CN | disclosed |
| EP-0028031-A1 | Novel quinazoline derivatives, a pharmaceutical composition containing such derivatives as active ingredient and a process for producing the quinazoline derivatives | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-05-06 | — | — | EP | disclosed |
| US-4005088-A | Process for the chemical separation of racemic modifications of α-aminocarboxylic acid derivatives, and cinchonidine salt intermediates | ANDENO B.V. (NL) | 1977-01-25 | — | — | US | disclosed |
| US-3987167-A | LYMPHOBLASTIC AND MYELOBLASTIC LEUKEMIAS | RHONE-POULENC S.A. (FR) | 1976-10-19 | — | — | US | disclosed |
| US-3987028-A | ANTITUMOR, STREPTOMYCES | RHONE-POULENC S.A. (FR) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252835-A1 | treatment of sleep disorders with five novel polymorphic forms of modafinil racemate called CRL 40476 form III, CRL 40476 form IV, CRL 40476 form V, CRL 40476 form VI, CRL 40476 form VII; preparing a new solvate of modafinil comprising dissolving in solvent and crystallizing | CYP4F11, NR1D1, CYP4F3 | TTR 1764/4885LMNA 3548/4885ALDH1A1 1028/4885 |
| US-20040102523-A1 | Modafinil polymorphic forms | GRIN3A, GRIN3B, COMT | TTR 1108/4885LMNA 3077/4885ALDH1A1 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.