Tetrahydrofuran

Tetrahydrofuran

SCHEMBL193538

C1CCOC1.ClC(Cl)Cl

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28748091 0.96 ALDH1A1 (0.61)
Tetrahydrofuran SCHEMBL2812148 0.89 ALDH1A1 (0.53)
Tetrahydrofuran SCHEMBL28820736 0.88
1,1,2,2-Tetrachloroethane SCHEMBL5687952 0.88 ALDH1A1 (0.61)
Tetrahydrofuran SCHEMBL2975678 0.85
Tetrahydrofuran SCHEMBL3618483 0.85 ALDH1A1 (0.57)
Dioxane SCHEMBL8899755 0.82 TTR (0.60)
Dioxane SCHEMBL194901 0.82 TTR (0.60)
SCHEMBL3093207 0.82 ALDH1A1 (0.53)
SCHEMBL3455441 0.82 ALDH1A1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114426701-B Preparation of P-N compound synergistic graphene oxide flame retardant and application of P-N compound synergistic graphene oxide flame retardant in epoxy resin 桂林理工大学 2023-08-15 CN claimed
CN-113979894-B Safe durable antibacterial natural textile material and preparation method thereof 北京工商大学 2023-06-23 CN claimed
CN-114426701-A Preparation of P-N compound and graphene oxide synergistic flame retardant and application of P-N compound and graphene oxide synergistic flame retardant in epoxy resin 桂林理工大学 2022-05-03 CN claimed
CN-113979894-A Safe and lasting antibacterial natural textile material and preparation method thereof 北京工商大学 2022-01-28 CN claimed
CN-112774733-A Cage-shaped supramolecular catalyst for catalyzing thioether oxidation and preparation method and application thereof 福州大学 2021-05-11 CN claimed
CN-112047831-A Monbunone crystallization process, single crystal and culture method thereof 天津市中升挑战生物科技有限公司 2020-12-08 CN claimed
CN-111072966-A Piperazine-based polythioamide resin and synthetic method thereof 白银图微新材料科技有限公司 2020-04-28 CN claimed
WO-2020068004-A2 ANTITUBERCULOSIS LANOSTANE TRITERPENOID AND METHOD OF MAKING THE COMPOUNDS NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY (TH) 2020-04-02 WO claimed
CN-110642854-A Polycrystalline form of fused ring compound, composition, preparation method and application thereof 成都克莱蒙医药科技有限公司 2020-01-03 CN claimed
CN-108864199-A The metal supermolecular gel rubber material and its synthetic method of a kind of temperature control variations in light and application 中山大学 2018-11-23 CN claimed
US-20180105668-A1 METHODS OF ISOLATING MELT-PROCESSIBLE POLYCARBONATE FROM PLASTIC WASTE, METHODS OF PREPARING POLYCARBONATE-CONTAINING HYBRID POLYMERS, AND COMPOSITIONS COMPRISING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2018-04-19 US claimed
CN-107325033-A A kind of method of high stereoselectivity synthesis aplysiatoxin Dap fragments 华东师范大学 2017-11-07 CN claimed
US-20160115142-A1 PROCESS FOR THE SYNTHESIS OF 5-HYDROXYMETHYLFURFURAL FROM SACCHARIDES NOVAMONT S.P.A. (IT) 2016-04-28 US claimed
JP-4718177-B2 2011-07-06 JP claimed
US-7405323-B2 Modafinil polymorphic forms CEPHALON FRANCE (FR) 2008-07-29 US claimed
US-20060252835-A1 treatment of sleep disorders with five novel polymorphic forms of modafinil racemate called CRL 40476 form III, CRL 40476 form IV, CRL 40476 form V, CRL 40476 form VI, CRL 40476 form VII; preparing a new solvate of modafinil comprising dissolving in solvent and crystallizing CEPHALON FRANCE (FR) 2006-11-09 US claimed
CN-1675177-A Modafinil polymorphic forms CEPHALON FRANCE (FR) 2005-09-28 CN claimed
US-20040102523-A1 Modafinil polymorphic forms TEVA SANTE (FR) 2004-05-27 US claimed
US-12037328-B2 Compounds containing benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxide or benzo[d][1,3]oxathiole 3,3-dioxide and methods/uses thereof as agonists of G protein-coupled receptor 119 PRAMANA PHARMACEUTICALS INC. (CA) 2024-07-16 US disclosed
US-3937720-A ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1976-02-10 US disclosed