Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810781 | 0.80 | LTA4H (0.55) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL8064264 | 0.80 | LTA4H (0.55) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL1810782 | 0.79 | PRSS1 (0.47) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL17210678 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1LMNASLC1A3 | |
| SCHEMBL27949535 | 0.77 | PRSS1 (0.46) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL43742 | 0.76 | KMT2A (0.61) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL22308234 | 0.76 | KMT2A (0.41) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL28497163 | 0.76 | PRSS1 (0.44) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL29165380 | 0.76 | PRSS1 (0.46) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL666850 | 0.76 | ALDH1A1 (0.48) | PRSS1PRSS2PRSS3KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795563-B2 | Particulate pharmaceutical composition | NANOCARRIER CO., LTD. (JP) | 2017-10-24 | — | — | US | disclosed |