Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618233 | 0.79 | HTT (0.48) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12574089 | 0.78 | TUBB1 (0.43) | TSHRCYP3A4GAAALDH1A1MEN1 | |
| SCHEMBL28607273 | 0.77 | KMT2A (0.45) | TSHRCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL14027974 | 0.76 | TSHR (0.64) | TSHRALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28332018 | 0.75 | POLB (0.55) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL28607669 | 0.75 | PLK1 (0.47) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL27501307 | 0.75 | MEN1 (0.59) | TSHRCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL13503685 | 0.72 | KMT2A (0.52) | TSHRMEN1KMT2APOLB | |
| SCHEMBL8943682 | 0.72 | CA2 (0.58) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10817091 | 0.71 | SLC22A6 (0.42) | TSHRCYP1A2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| US-9029446-B2 | Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization | BASF SE (DE) | 2015-05-12 | — | — | US | disclosed |
| EP-2510047-B1 | CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION | BASF SE (DE) | 2014-11-05 | — | — | EP | disclosed |
| US-8415416-B2 | Electret materials | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |
| US-20130012091-A1 | Electret Materials | BASF SE (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20120184170-A1 | Electret Materials | CHIN HUI (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110136950-A1 | Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization | BASF SE (DE) | 2011-06-09 | — | — | US | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20080249269-A1 | Electret materials | CIBA CORP. | 2008-10-09 | — | — | US | disclosed |
| US-20070149663-A1 | Resin compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-28 | — | — | US | disclosed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |