Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607273 | 0.87 | KMT2A (0.45) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28618233 | 0.87 | HTT (0.48) | CHEK1PIM1MAPK8CLK4KMT2A | |
| SCHEMBL28617559 | 0.81 | PLK1 (0.44) | PLK1MTNR1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL28609649 | 0.80 | GAA (0.46) | PLK1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL1949545 | 0.75 | TSHR (0.47) | KMT2AMEN1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28618236 | 0.72 | GAA (0.44) | PLK1L3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28281092 | 0.70 | HTT (0.50) | CHEK1PIM1MAPK8CLK4KMT2A | |
| SCHEMBL28605595 | 0.70 | SLC6A2 (0.51) | MTNR1AKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL353828 | 0.70 | CTSD (0.70) | PLK1TSHRALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28281093 | 0.69 | LMNA (0.47) | CHEK1PIM1MAPK8CLK4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248399-A | O-amino aromatic amide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-08-13 | — | — | CN | disclosed |