Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18891691 | 0.89 | CES2 (0.39) | CES2CES1TAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL9286802 | 0.85 | TSHR (0.38) | HDAC3HDAC1HDAC2TAS1R3TAS1R1 | |
| SCHEMBL9229150 | 0.85 | TSHR (0.38) | HDAC3HDAC1HDAC2TAS1R3TAS1R1 | |
| SCHEMBL9231510 | 0.84 | ALDH1A1 (0.33) | TAS1R3TAS1R1TAS1R2KCNH2SMN1; SMN2 | |
| SCHEMBL9281513 | 0.84 | ALDH1A1 (0.33) | TAS1R3TAS1R1TAS1R2KCNH2SMN1; SMN2 | |
| SCHEMBL7786189 | 0.82 | CES2 (0.44) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL18533077 | 0.81 | TSHR (0.50) | CES2CES1HDAC2HDAC8TSHR | |
| SCHEMBL21259631 | 0.81 | TSHR (0.50) | CES2CES1HDAC2HDAC8TSHR | |
| SCHEMBL15301598 | 0.81 | CES2 (0.36) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL16951255 | 0.81 | CES2 (0.36) | CES2CES1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235895-A1 | LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-10-25 | — | — | EP | disclosed |