Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746393 | 0.95 | CES2 (0.42) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL4290441 | 0.93 | PPARG (0.42) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL4825249 | 0.93 | PPARG (0.42) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL8746416 | 0.93 | PPARG (0.42) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL7523840 | 0.93 | PPARG (0.42) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL10091381 | 0.91 | CES2 (0.45) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL7526784 | 0.86 | PPARG (0.38) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL6630352 | 0.85 | ALDH1A1 (0.42) | CES2CES1ALDH1A1KDM4EHDAC3 | |
| SCHEMBL21605359 | 0.84 | ALDH1A1 (0.36) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL14510529 | 0.84 | CES2 (0.42) | CES2CES1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |
| US-5683623-A | FERROELECTRIC LIQUID CRYSTALS CELLS AND DEVICES FOR ELECTROOPTICAL APPARATUS | CENTRAL RESEARCH LABORATORIES LIMITED (GB) | 1997-11-04 | — | — | US | disclosed |
| EP-0662114-B1 | DIOXANE DERIVATIVES | CENTRAL RESEARCH LAB LTD (GB) | 1997-02-19 | — | — | EP | disclosed |