SCHEMBL1949783

SCHEMBL1949783

Cc1ccc(/N=C/c2cc([N+](=O)[O-])ccc2O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.67
FNTB P49356 1/20 0.67
MAPT P10636 8/20 0.62
ALDH1A1 P00352 6/20 0.62
GAA P10253 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
HPGD P15428 2/20 0.62
MAOB P27338 1/20 0.61
POLB P06746 4/20 0.60
PKM P14618 1/20 0.58
LMNA P02545 4/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
HTT P42858 3/20 0.56
KDM4E B2RXH2 2/20 0.56
ERN1 O75460 1/20 0.55
NPC1 O15118 3/20 0.54
RAB9A P51151 2/20 0.54
HCRTR1 O43613 1/20 0.53
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1949785 1.00 FNTA (0.67) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL22624833 0.89 FNTA (0.70) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL1950799 0.86 FNTA (0.67) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL1950800 0.86 FNTA (0.67) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL22624760 0.86 FNTA (0.67) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL14011737 0.86 FNTA (0.79) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL22611887 0.86 FNTA (0.79) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL22624745 0.85 FNTA (0.63) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL22624740 0.85 MAOB (0.67) FNTAFNTBMAPTALDH1A1GAA
SCHEMBL12416797 0.85 POLB (0.64) FNTAFNTBMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3737664-B1 ANTIMICROBIAL 2-[[(PHENYL)IMINO]METHYL]-4-NITRO-PHENOL DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE NUSB-NUSE INTERACTION OF MICROORGANISMS FOR THE TREATMENT OF BACTERIAL INFECTIONS UNIV HONG KONG POLYTECHNIC (CN) 2024-04-10 EP disclosed
US-20210317076-A9 COMPOUNDS WITH ANTIMICROBIAL ACTIVITY THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2021-10-14 US disclosed
US-20200347010-A1 COMPOUNDS WITH ANTIMICROBIAL ACTIVITY UNIV HONG KONG POLYTECHNIC (CN) 2020-11-05 US disclosed
EP-2151446-B1 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand RIMTEC CORP (JP) 2016-04-13 EP disclosed
EP-2151445-B1 Process for the preparation of bidentate Schiff base ruthenium catalysts containing a salicylaldimine-type ligand RIMTEC CORP (JP) 2015-02-18 EP disclosed
US-8338613-B2 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand RIMTEC CORPORATION (JP) 2012-12-25 US disclosed
US-20110137043-A1 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand TELENE S.A.S. (FR) 2011-06-09 US disclosed
US-20110065925-A1 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand TELENE S.A.S. (FR) 2011-03-17 US disclosed
EP-2151446-A1 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand Telene SAS (FR) 2010-02-10 EP disclosed
EP-2151445-A1 Process for the preparation of bidentate Schiff base ruthenium cataysts containing a saliclyldimine-type ligand Telene SAS (FR) 2010-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200347010-A1 COMPOUNDS WITH ANTIMICROBIAL ACTIVITY CFTR, FPR3, FPR1 FNTA 3978/4885FNTB 3723/4885MAPT 4046/4885
US-20210317076-A9 COMPOUNDS WITH ANTIMICROBIAL ACTIVITY CFTR, FPR3, FPR1 FNTA 3978/4885FNTB 3723/4885MAPT 4046/4885
US-20110137043-A1 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand SPR, LIG4, SUCLA2 FNTA 1072/4885FNTB 2122/4885MAPT 3633/4885
US-20110065925-A1 Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand SPR, LIG4, SUCLA2 FNTA 1072/4885FNTB 2122/4885MAPT 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.