Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.83 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.83 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.83 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.83 |
| ▸ | APAF1 | O14727 | 2/20 | 0.83 |
| ▸ | NSD2 | O96028 | 2/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.83 |
| ▸ | TDP2 | O95551 | 1/20 | 0.65 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.65 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.65 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412940 | 0.91 | CASP3 (1.00) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL679695 | 0.91 | CASP3 (1.00) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL129810 | 0.88 | CASP3 (0.65) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL21690572 | 0.80 | CASP3 (0.79) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL23457757 | 0.80 | CASP3 (0.78) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL23458028 | 0.80 | CASP3 (0.78) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL21690569 | 0.79 | CASP3 (0.77) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL23458036 | 0.78 | CASP3 (0.76) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL23457440 | 0.77 | CASP3 (0.74) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL2463171 | 0.76 | CASP3 (0.71) | CASP3SENP6SENP8SENP7APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227966-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-23 | — | — | US | disclosed |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2010127307-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | CASP3 83/4885SENP6 2656/4885SENP8 3285/4885 |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | CASP3 82/4885SENP6 2580/4885SENP8 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.