SCHEMBL679695

SCHEMBL679695

COc1ccc(C(=O)c2nccc3cc(OC)c(OC)cc23)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 1.00
SENP6 Q9GZR1 4/20 1.00
SENP8 Q96LD8 3/20 1.00
SENP7 Q9BQF6 3/20 1.00
APAF1 O14727 2/20 1.00
NSD2 O96028 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
KDM4E B2RXH2 2/20 0.70
TDP2 O95551 1/20 0.64
PPP1CA P62136 1/20 0.64
SAE1 Q9UBE0 1/20 0.64
UBA2 Q9UBT2 1/20 0.64
LMNA P02545 3/20 0.59
CYP3A4 P08684 3/20 0.57
CYP1A2 P05177 2/20 0.57
CYP2C9 P11712 2/20 0.57
TSHR P16473 2/20 0.57
CYP2C19 P33261 2/20 0.57
IGFBP3 P17936 2/20 0.55
PDE10A Q9Y233 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412940 1.00 CASP3 (1.00) CASP3SENP6SENP8SENP7APAF1
SCHEMBL194997 0.91 CASP3 (0.83) CASP3SENP6SENP8SENP7APAF1
SCHEMBL21690572 0.88 CASP3 (0.79) CASP3SENP6SENP8SENP7APAF1
SCHEMBL23457757 0.88 CASP3 (0.78) CASP3SENP6SENP8SENP7APAF1
SCHEMBL23458028 0.88 CASP3 (0.78) CASP3SENP6SENP8SENP7APAF1
SCHEMBL21690569 0.87 CASP3 (0.77) CASP3SENP6SENP8SENP7APAF1
SCHEMBL23458036 0.86 CASP3 (0.76) CASP3SENP6SENP8SENP7APAF1
SCHEMBL23457440 0.85 CASP3 (0.74) CASP3SENP6SENP8SENP7APAF1
SCHEMBL2463171 0.83 CASP3 (0.71) CASP3SENP6SENP8SENP7APAF1
SCHEMBL21690825 0.83 CASP3 (0.70) CASP3SENP6SENP8SENP7APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4229639-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS Global Biopharma, Inc. (CA) 2023-08-23 EP claimed
WO-2022081889-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-21 WO claimed
US-20160184232-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans MALLINCKRODT BRAND PHARMACEUTICALS LLC (F/K/A MALLINCKRODT BRAND PHARMACEUTICALS, INC.) 2016-06-30 US claimed
CN-103402499-A Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans MALLINCKRODT LLC 2013-11-20 CN claimed
EP-2654727-A1 METHODS OF PRODUCING STABILIZED SOLID DOSAGE PHARMACEUTICAL COMPOSITIONS CONTAINING MORPHINANS Mallinckrodt LLC (US) 2013-10-30 EP claimed
US-20130273153-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans MNK 2011 LLC (F/K/A MALLINCKRODT INC.) 2013-10-17 US claimed
WO-2012087377-A1 METHODS OF PRODUCING STABILIZED SOLID DOSAGE PHARMACEUTICAL COMPOSITIONS CONTAINING MORPHINANS MALLINCKRODT LLC (US) 2012-06-28 WO claimed
US-20110287095-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans Mallinkckrodt Inc. (US) 2011-11-24 US claimed
WO-2011087765-A2 METHODS OF PRODUCING STABILIZED SOLID PHARMACEUTICAL COMPOSITIONS CONTAINING MORPHINANS MALLINCKRODT INC. (US) 2011-07-21 WO claimed
US-20110150989-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans Mallinkckrodt Inc. (US) 2011-06-23 US claimed
WO-2011041470-A2 SUSTAINED-RELEASE OPIATE AND OPIATE DERIVATIVE COMPOSITIONS MALLINCKRODT INC. (US) 2011-04-07 WO claimed
US-20110077222-A1 Sustained-Release Opiate and Opiate Derivative Compositions MALLINCKRODT INC. (US) 2011-03-31 US claimed
JP-63310813-A None JP disclosed
CN-119684549-A Covalent organic framework material solid-phase microextraction fiber and application thereof in alkaloid metabolism and neurotransmitter analysis 河南中医药大学 2025-03-25 CN disclosed
EP-4229639-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS Global Biopharma, Inc. (CA) 2023-08-23 EP disclosed
US-20220130493-A1 METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE GBS GLOBAL BIOPHARMA, INC. (CA) 2022-04-28 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4018927-A Treatment of proliferating skin diseases with papaverine alkaloids THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150989-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans LPXN, FSCN1, NCLN CASP3 2942/4885SENP6 1681/4885SENP8 1190/4885
US-20110287095-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans LPXN, FSCN1, NCLN CASP3 2942/4885SENP6 1681/4885SENP8 1190/4885
US-20110077222-A1 Sustained-Release Opiate and Opiate Derivative Compositions OPRL1, OPRK1, OPRM1 CASP3 4726/4885SENP6 351/4885SENP8 1044/4885
US-20130273153-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans LPXN, FSCN1, NCLN CASP3 2942/4885SENP6 1681/4885SENP8 1190/4885
US-20160184232-A1 Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans LPXN, FSCN1, NCLN CASP3 2942/4885SENP6 1681/4885SENP8 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.