Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.80 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.63 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178425 | 0.93 | RAB9A (0.85) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL19491372 | 0.92 | SIRT1 (0.79) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL12010921 | 0.91 | SIRT1 (0.92) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL12113118 | 0.91 | SIRT1 (0.92) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL13211986 | 0.90 | NPC1 (0.80) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL16589432 | 0.90 | PTPN1 (0.80) | NPC1RAB9AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL82305 | 0.89 | RAB9A (1.00) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL366747 | 0.89 | SMN1; SMN2 (0.74) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| SCHEMBL19491368 | 0.89 | NPC1 (0.63) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 | |
| Iodide SCHEMBL30758618 | 0.87 | RAB9A (0.96) | NPC1RAB9AMAPTSMN1; SMN2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343438-B2 | Heat-sensitive recording material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170297355-A1 | Heat-Sensitive Recording Material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170297355-A1 | Heat-Sensitive Recording Material | SCN1A, SCN3A, KCNN3 | NPC1 3839/4885RAB9A 1511/4885MAPT 796/4885 |
| US-10343438-B2 | Heat-sensitive recording material | SCN1A, SCN3A, KCNN3 | NPC1 3839/4885RAB9A 1511/4885MAPT 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.