SCHEMBL19502219

SCHEMBL19502219

Clc1ccc2c(c1)oc1cccc(Cl)c12

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AHR P35869 13/20 0.63
TTR P02766 3/20 0.49
MCL1 Q07820 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CDC25A P30304 1/20 0.39
CDC25C P30307 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19802263 0.81 AHR (0.59) AHRTTRMCL1CA1CA2
SCHEMBL21638102 0.81 TTR (0.47) AHRTTRCDC25ACDC25C
SCHEMBL21191893 0.81 AHR (0.59) AHRTTRMCL1CA1CA2
SCHEMBL24727144 0.81 TTR (0.47) AHRTTRCDC25ACDC25C
SCHEMBL22156332 0.81 TTR (0.47) AHRTTR
SCHEMBL24343623 0.81 ALDH1A1 (0.59) TTR
SCHEMBL21669068 0.81 AHR (0.59) AHRTTRMCL1CA1CA2
SCHEMBL23203595 0.81 TTR (0.47) AHRTTR
SCHEMBL21110463 0.81 AHR (0.59) AHRTTRMCL1
SCHEMBL2966509 0.81 AHR (0.59) AHRTTRMCL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140257-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-05-05 US disclosed
US-20190165282-A1 HETEROCYCLIC COMPOUNDS COMPRISING DIBENZOFURAN AND/OR DIBENZOTHIOPHENE STRUCTURES MERCK PATENT GMBH (DE) 2019-05-30 US disclosed
WO-2017178311-A1 HETEROCYCLIC COMPOUNDS COMPRISING DIBENZOFURAN AND/OR DIBENZOTHIOPHENE STRUCTURES MERCK PATENT GMBH (DE) 2017-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220140257-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD2, OCIAD1, OXER1 AHR 1915/4885TTR 2530/4885MCL1 4523/4885
US-20190165282-A1 HETEROCYCLIC COMPOUNDS COMPRISING DIBENZOFURAN AND/OR DIBENZOTHIOPHENE STRUCTURES DDT, NUDT1, ETFB AHR 959/4885TTR 1769/4885MCL1 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.