Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475365 | 0.90 | TLR7 (0.42) | TLR7RXFP1PIK3R1PIK3CAKMT2A | |
| SCHEMBL22445197 | 0.83 | AGTR1 (0.42) | TLR7ALDH1A1KMT2AMAPTADORA3 | |
| SCHEMBL19503120 | 0.82 | TLR7 (0.49) | TLR7RXFP1ALDH1A1KMT2AADORA3 | |
| SCHEMBL26981077 | 0.82 | TLR7 (0.59) | TLR7RXFP1ADORA3TLR8 | |
| SCHEMBL29280827 | 0.81 | LMNA (0.49) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL30842222 | 0.81 | LMNA (0.49) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL30842204 | 0.79 | TSPO (0.40) | PIK3R1PIK3CAALDH1A1KMT2AMAPT | |
| SCHEMBL20741496 | 0.79 | TSPO (0.40) | PIK3R1PIK3CAALDH1A1KMT2AMAPT | |
| SCHEMBL20475984 | 0.78 | KCNH2 (0.42) | PIK3R1PIK3CAALDH1A1KMT2AMAPT | |
| SCHEMBL30842202 | 0.78 | KCNH2 (0.42) | PIK3R1PIK3CAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184746-A1 | NLRP3 MODULATORS | IFM THERAPEUTICS, INC (US) | 2017-10-26 | — | — | WO | disclosed |