Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 5/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.51 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.43 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257339 | 0.84 | P2RX3 (0.53) | P2RY1P2RY2P2RX3P2RX2P2RX4 | |
| SCHEMBL21257373 | 0.78 | YTHDC1 (0.62) | P2RY1YTHDC1 | |
| SCHEMBL19503343 | 0.77 | P2RY1 (0.59) | P2RY1P2RY2PDE4APDE4BPDE4C | |
| SCHEMBL19503301 | 0.76 | P2RY1 (0.58) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL24320810 | 0.75 | P2RY1 (0.57) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL1064092 | 0.74 | POLB (0.61) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL29664985 | 0.74 | POLB (0.61) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL3637334 | 0.74 | POLB (0.61) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL15721195 | 0.74 | POLB (0.61) | P2RY1P2RY2GPR17P2RX3P2RX2 | |
| SCHEMBL25613500 | 0.72 | P2RY1 (0.52) | P2RY1P2RY2GPR17P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017185061-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |