Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18893340 | 0.94 | MAPT (0.39) | MAPTLMNASMN1; SMN2TSHRHTT | |
| SCHEMBL22431621 | 0.91 | MAPT (0.38) | MAPTLMNASMN1; SMN2TSHRHTT | |
| SCHEMBL16411393 | 0.78 | SLC6A3 (0.36) | TSHRHTTSLC6A3ALDH1A1TDP1 | |
| SCHEMBL18884252 | 0.75 | KCNH2 (0.50) | MAPTLMNASMN1; SMN2TSHRHTT | |
| SCHEMBL8697797 | 0.75 | KCNH2 (0.50) | MAPTLMNASMN1; SMN2TSHRHTT | |
| SCHEMBL18893282 | 0.75 | SLC6A3 (0.37) | LMNASLC6A3 | |
| SCHEMBL18893329 | 0.74 | LMNA (0.35) | LMNASMN1; SMN2TSHRHTTSLC6A3 | |
| SCHEMBL21776299 | 0.72 | SLC6A3 (0.40) | LMNASMN1; SMN2TSHRHTTSLC6A3 | |
| SCHEMBL18647864 | 0.71 | LMNA (0.35) | MAPTLMNASMN1; SMN2TSHRHTT | |
| SCHEMBL18884234 | 0.71 | LMNA (0.35) | MAPTLMNASMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305893-A1 | HETEROCYCLIC COMPOUNDS AS DCTPP1 MODULATORS | THOMAS HELLEDAYS STIFTELSE FOR MEDICINSK FORSKNING (SE) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305893-A1 | HETEROCYCLIC COMPOUNDS AS DCTPP1 MODULATORS | DCTPP1, ENPP1, PPA1 | MAPT 3017/4885LMNA 4551/4885SMN1; SMN2 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.