Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19504485 | 0.83 | CCNA2 (0.40) | CCNA2CDK2CCNA1AURKAHRH4 | |
| SCHEMBL18818491 | 0.74 | CCNA2 (0.39) | CCNA2CDK2CCNA1AURKAHRH4 | |
| SCHEMBL21657033 | 0.72 | HSP90AA1 (0.50) | MAPK1MEN1KMT2AHSP90AA1ALDH1A1 | |
| SCHEMBL23029553 | 0.71 | CDK5 (0.61) | CCNA2CDK2MAPK1CDK1MAPT | |
| SCHEMBL12840807 | 0.71 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL12497252 | 0.71 | HTR2C (0.46) | CCNA2CDK2CCNA1AURKAMAPK1 | |
| SCHEMBL19498176 | 0.70 | HSP90AA1 (0.42) | HRH4MAPK1MEN1KMT2AHSP90AA1 | |
| SCHEMBL18818985 | 0.69 | MAPK1 (0.40) | MAPK1MEN1KMT2AHSP90AA1MKNK1 | |
| SCHEMBL14983698 | 0.67 | GAA (0.50) | CCNA2CDK2CCNA1AURKAMAPK1 | |
| SCHEMBL16474029 | 0.67 | ENPP2 (0.62) | HRH4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | CARM1, ADRM1, PRMT1 | CCNA2 2692/4885CDK2 1049/4885CCNA1 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.