Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.33 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505137 | 0.91 | ADORA1 (0.41) | ADORA1P2RX3FAAHTRPC1TRPC4 | |
| SCHEMBL19505293 | 0.82 | ADORA1 (0.38) | ADORA1P2RX3TRPC1TRPC4TRPC5 | |
| SCHEMBL19505070 | 0.80 | TRPC5 (0.52) | P2RX3TRPC1TRPC4TRPC5 | |
| SCHEMBL19560542 | 0.79 | TRPC4 (0.44) | ADORA1P2RX3TRPC1TRPC4TRPC5 | |
| SCHEMBL18835155 | 0.77 | TRPC5 (0.48) | GRIN1GRIN2BP2RX3EGLN1TRPC1 | |
| SCHEMBL19375179 | 0.77 | ADORA1 (0.38) | ADORA1P2RX3TRPC1TRPC4TRPC5 | |
| SCHEMBL16076156 | 0.76 | TRPC4 (0.56) | ADORA1TRPC1TRPC4TRPC5MAPT | |
| SCHEMBL21316296 | 0.76 | TRPC5 (0.45) | ADORA1P2RX3TRPC1TRPC4TRPC5 | |
| SCHEMBL19505599 | 0.75 | GRIN2B (0.38) | ADORA1GRIN1GRIN2BP2RX3TRPC1 | |
| SCHEMBL21499635 | 0.75 | P2RX3 (0.43) | P2RX3TRPC1TRPC4TRPC5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969736-B2 | Substituted xanthines and methods of use thereof | HYDRA BIOSCIENCES, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170305910-A1 | Substituted Xanthines and Methods of Use Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305910-A1 | Substituted Xanthines and Methods of Use Thereof | TRPC5, TRPC7, TRPC4 | ADORA1 841/4885GRIN1 388/4885GRIN2B 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.