Biphenyl

Biphenyl

SCHEMBL1950563

CC1CO1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.46
CYP1A2 P05177 1/20 0.43
GRM2 Q14416 1/20 0.41
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
SLC6A4 P31645 1/20 0.40
CHRM2 P08172 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
KDM1A O60341 2/20 0.38
MAOB P27338 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL10879900 0.82 TSHR (0.38) TSHRCHRM2MEN1CYP2C19KMT2A
Propylene Oxide SCHEMBL29238686 0.81 NPC1 (0.41) ALDH1A1TSHRCYP1A2GRM2SMN1; SMN2
Toluene SCHEMBL27963582 0.81 ACHE (0.58) ALDH1A1TSHRSMN1; SMN2MEN1CYP2C19
Chlorobenzene SCHEMBL29027164 0.81 TSHR (0.58) ALDH1A1TSHRCYP1A2SLC6A4MEN1
SCHEMBL15274537 0.80 CHRM2 (0.57) TSHRCHRM2TAAR1KDM1AMAOB
Phenol SCHEMBL1224881 0.79 CA12 (0.55) ALDH1A1TSHRMEN1CYP2C19KMT2A
Aniline SCHEMBL9226304 0.79 TSHR (0.55) ALDH1A1TSHRCYP1A2MEN1CYP2C19
Phenol SCHEMBL1738526 0.79 CA12 (0.55) ALDH1A1TSHRMEN1CYP2C19KMT2A
Benzene SCHEMBL28146919 0.78 TSHR (0.36) TSHRCHRM2MEN1CYP2C19KMT2A
Biphenyl SCHEMBL28384213 0.78 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104926704-B Aziridine class compound and preparation method thereof 浙江九洲药物科技有限公司 2019-03-05 CN claimed
CN-104926704-A Nitrogen heterocyclic propane compound and preparation method thereof ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD 2015-09-23 CN claimed
CN-109804305-A Liquid-crystal apparatus and its manufacturing method JSR株式会社 2019-05-24 CN disclosed
CN-104926704-B Aziridine class compound and preparation method thereof 浙江九洲药物科技有限公司 2019-03-05 CN disclosed
CN-104926704-B Aziridine class compound and preparation method thereof 浙江九洲药物科技有限公司 2019-03-05 CN disclosed
CN-104926704-A Nitrogen heterocyclic propane compound and preparation method thereof ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD 2015-09-23 CN disclosed
CN-102124063-A Anticorrosive coating composition and anticorrosive coating film structure using same SHOWA DENKO KK 2011-07-13 CN disclosed
US-20110135943-A1 ANTICORROSIVE COATING COMPOSITION AND ANTICORROSIVE COATING STRUCTURE USING SAME SHOWA DENKO K.K. (JP) 2011-06-09 US disclosed