Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505786 | 1.00 | HTT (0.48) | HTTTSHRLMNAHSD11B1KMT2A | |
| SCHEMBL19475152 | 0.88 | HTT (0.49) | HTTTSHRLMNAHSD11B1KMT2A | |
| SCHEMBL19505793 | 0.87 | TSHR (0.38) | HTTTSHRLMNAHSD11B1KMT2A | |
| SCHEMBL19505792 | 0.85 | LMNA (0.44) | TSHRLMNAKMT2AALDH1A1MGLL | |
| SCHEMBL19506099 | 0.82 | HTT (0.51) | HTTTSHRLMNAHSD11B1KMT2A | |
| SCHEMBL19505803 | 0.82 | KMT2A (0.53) | TSHRKMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19505791 | 0.80 | NPSR1 (0.36) | HTTTSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL19506192 | 0.77 | FKBP1A (0.50) | LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19506188 | 0.77 | FKBP1A (0.50) | LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19505801 | 0.75 | CA1 (0.42) | TSHRLMNAKMT2AALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |