Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505803 | 0.87 | KMT2A (0.53) | KMT2ATSHRALDH1A1MEN1POLB | |
| SCHEMBL19475006 | 0.81 | CA2 (0.39) | CA1CA2CA12CA7CA9 | |
| SCHEMBL19505792 | 0.79 | LMNA (0.44) | KMT2ATSHRALDH1A1MEN1MAPT | |
| SCHEMBL19505790 | 0.77 | CA12 (0.42) | CA1CA2CA12CA7CA9 | |
| SCHEMBL19506192 | 0.76 | FKBP1A (0.50) | ALDH1A1POLBLMNAGAAMMP2 | |
| SCHEMBL19506188 | 0.76 | FKBP1A (0.50) | ALDH1A1POLBLMNAGAAMMP2 | |
| SCHEMBL19505786 | 0.75 | HTT (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL19505783 | 0.75 | HTT (0.48) | CA1CA2CA12CA7CA9 | |
| SCHEMBL19505797 | 0.71 | MMP2 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL20996809 | 0.71 | CA1 (0.36) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |