Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20996813 | 0.85 | POLB (0.32) | MMP2ANPEP | |
| SCHEMBL19475321 | 0.85 | POLB (0.32) | MMP2ANPEP | |
| SCHEMBL19505918 | 0.81 | CFTR (0.40) | MMP2ANPEP | |
| SCHEMBL19505986 | 0.81 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL19506111 | 0.76 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL19475763 | 0.73 | NFKB1 (0.33) | PTPN1 | |
| SCHEMBL19475762 | 0.73 | NFKB1 (0.33) | PTPN1 | |
| SCHEMBL19475132 | 0.71 | GRM5 (0.42) | — | |
| SCHEMBL19475038 | 0.71 | L3MBTL1 (0.45) | — | |
| SCHEMBL19505800 | 0.71 | CA12 (0.41) | PTPN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |