Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475762 | 0.91 | NFKB1 (0.33) | PTPN1NFKB1NFKB2RELA | |
| SCHEMBL19475763 | 0.91 | NFKB1 (0.33) | PTPN1NFKB1NFKB2RELA | |
| SCHEMBL19505791 | 0.86 | NPSR1 (0.36) | KMT2A | |
| SCHEMBL19474997 | 0.84 | L3MBTL1 (0.31) | — | |
| SCHEMBL19474996 | 0.84 | L3MBTL1 (0.31) | — | |
| SCHEMBL19475399 | 0.83 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL19475397 | 0.83 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL19505788 | 0.81 | L3MBTL1 (0.36) | KMT2A | |
| SCHEMBL19506112 | 0.81 | MMP2 (0.35) | PTPN1 | |
| SCHEMBL19505807 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |