Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994085 | 0.84 | MAPK1 (0.46) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL7654284 | 0.80 | L3MBTL1 (0.55) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7104442 | 0.80 | DDB1 (0.52) | KDM4EALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL7963575 | 0.75 | PDCD1 (0.43) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL16958368 | 0.75 | PDCD1 (0.46) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21381349 | 0.74 | MAPT (0.49) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2354192 | 0.73 | PDCD1 (0.47) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL17156171 | 0.73 | MAPT (0.55) | KDM4EALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL1949598 | 0.72 | PTGDR2 (0.46) | KDM4EALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL2714960 | 0.71 | PDCD1 (0.42) | KDM4EMAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136801-A1 | Novel Compounds | DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136801-A1 | Novel Compounds | C1R, RB1, CNKSR1 | KDM4E 3006/4885ALDH1A1 173/4885TSHR 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.