Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379717 | 0.86 | L3MBTL1 (0.63) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL7994085 | 0.84 | MAPK1 (0.46) | L3MBTL1KDM4EALDH1A1TDP1POLB | |
| SCHEMBL3409855 | 0.82 | L3MBTL1 (0.67) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL19519819 | 0.81 | KDM4E (0.56) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL2059383 | 0.81 | POLB (0.58) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL7104442 | 0.80 | DDB1 (0.52) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL1950706 | 0.80 | KDM4E (0.49) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL6746949 | 0.79 | L3MBTL1 (0.56) | L3MBTL1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL2354192 | 0.79 | PDCD1 (0.47) | L3MBTL1KDM4EALDH1A1TDP1POLB | |
| SCHEMBL19086322 | 0.79 | PTGDR2 (0.61) | L3MBTL1KDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |