Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963964 | 0.86 | LMNA (0.46) | MAPK1TDP1L3MBTL1PPARDKMT2A | |
| SCHEMBL10422938 | 0.85 | PPARD (0.55) | L3MBTL1PPARDKMT2ALMNACYP1A2 | |
| SCHEMBL7654284 | 0.84 | L3MBTL1 (0.55) | TDP1L3MBTL1PLA2G1BALDH1A1KDM4E | |
| SCHEMBL1950706 | 0.84 | KDM4E (0.49) | MAPK1TDP1L3MBTL1KMT2ACYP1A2 | |
| SCHEMBL7104442 | 0.84 | DDB1 (0.52) | MAPK1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7104178 | 0.83 | LMNA (0.50) | MAPK1L3MBTL1PPARDKMT2ALMNA | |
| SCHEMBL15518189 | 0.82 | ALDH1A1 (0.58) | MAPK1TDP1L3MBTL1KMT2ALMNA | |
| SCHEMBL1706851 | 0.79 | LMNA (0.45) | MAPK1TDP1L3MBTL1KMT2ALMNA | |
| SCHEMBL19086323 | 0.79 | PLA2G1B (0.52) | MAPK1TDP1L3MBTL1KMT2ALMNA | |
| SCHEMBL31359444 | 0.79 | PLA2G1B (0.52) | MAPK1TDP1L3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |