Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 8/20 | 0.32 |
| ▸ | CA12 | O43570 | 6/20 | 0.32 |
| ▸ | CA9 | Q16790 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000296 | 0.79 | CA2 (0.48) | CA2CA1CA12CA9CA4 | |
| SCHEMBL19475264 | 0.77 | TDP1 (0.34) | CA2TDP1CA1CA12CA9 | |
| SCHEMBL19475047 | 0.73 | CA2 (0.44) | CA2CA1CA12CA9CA4 | |
| SCHEMBL21962465 | 0.68 | CA2 (0.38) | CA2CA1CA12CA9ACSS2 | |
| SCHEMBL19507070 | 0.68 | LOXL2 (0.34) | CA2CA1CA12CA9LMNA | |
| SCHEMBL25590473 | 0.67 | FOLH1 (0.49) | TDP1LMNA | |
| SCHEMBL13668045 | 0.67 | PYCR1 (0.33) | — | |
| SCHEMBL8157066 | 0.67 | KMT2A (0.37) | CA2CA1LMNA | |
| SCHEMBL28120836 | 0.66 | CA2 (0.53) | CA2CA1CA12CA9CA4 | |
| SCHEMBL24478007 | 0.66 | CA2 (0.52) | CA2CA1CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184604-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | IFM THERAPEUTICS, INC (US) | 2017-10-26 | — | — | WO | disclosed |