Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946458 | 0.78 | LMNA (0.41) | TSHRLMNATAAR1HTR2AHRH1 | |
| SCHEMBL18929946 | 0.78 | TSHR (0.44) | TSHRLMNATAAR1HTR2AHRH1 | |
| SCHEMBL691655 | 0.77 | TRPA1 (0.47) | TSHRLMNATAAR1HTR2ATRPA1 | |
| SCHEMBL691654 | 0.77 | TRPA1 (0.47) | TSHRLMNATAAR1HTR2ATRPA1 | |
| SCHEMBL6568105 | 0.76 | TSHR (0.46) | TSHRLMNATAAR1HTR2AHRH1 | |
| SCHEMBL96430 | 0.75 | LMNA (0.48) | LMNATRPA1ALDH1A1 | |
| SCHEMBL2243794 | 0.75 | LMNA (0.48) | LMNATRPA1ALDH1A1 | |
| SCHEMBL1101279 | 0.75 | DPP4 (0.41) | LMNATAAR1HTR2A | |
| SCHEMBL9774973 | 0.73 | TSHR (0.48) | TSHRLMNATAAR1HTR2AHRH1 | |
| SCHEMBL11880021 | 0.73 | TSHR (0.48) | TSHRLMNATAAR1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2138230-B1 | Free Radical Post-Crosslinked Adsorbent and Method of Preparation | ROHM & HAAS (US) | 2015-01-21 | — | — | EP | disclosed |
| US-8076384-B2 | Free radical post-crosslinked adsorbent and method of preparation | ROHM AND HAAS COMPANY (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110136926-A1 | Catalysts for Olefin Hydration and Method of Preparation | ROHM AND HAAS COMPANY | 2011-06-09 | — | — | US | disclosed |
| US-20090326086-A1 | Free radical post-crosslinked adsorbent and method of preparation | ROHM AND HAAS COMPANY | 2009-12-31 | — | — | US | disclosed |
| US-20090325798-A1 | Friedel-crafts post-crosslinked adsorbent and method of preparation | XU MANCAI | 2009-12-31 | — | — | US | disclosed |
| EP-2138230-A2 | Free Radical Post-Crosslinked Adsorbent and Method of Preparation | Rohm and Haas Company (US) | 2009-12-30 | — | — | EP | disclosed |
| EP-2138229-A2 | Friedel-Crafts Post-Crosslinked Adsorbent and Method of Preparation | Rohm and Haas Company (US) | 2009-12-30 | — | — | EP | disclosed |